← brief for 2026-08-29 · Nutrition & lifestyle

The Role of SGLT2 Inhibitors in the Prevention of Type 2 Diabetes: A Narrative Review of Current Evidence.

Key takeaways

SGLT2 inhibitors — drugs like canagliflozin that lower blood sugar by making the kidneys flush out extra glucose — helped delay type 2 diabetes in people with prediabetes, but the evidence comes from observational studies and small trials, not large randomized tests. This means the link is strong but not proven as a cause-and-effect treatment benefit for everyone with prediabetes.

Who did this work

Owczarczyk-Durma AC · Blicharska M · Czupryniak L

Source

Article · PubMed, CKD nutrition RCTs · 2026 Aug 29
https://pubmed.ncbi.nlm.nih.gov/42667546/