← brief for 2026-08-29 · Slowing decline

Kidney biopsy unveiled: multifactorial damage in immune checkpoint inhibitor therapy, a case report

Key takeaways

A doctor described two patients who developed serious kidney scarring after receiving immune checkpoint inhibitors — drugs like Keytruda or Opdivo used for cancer. The patients had no prior kidney problems, and the damage appeared quickly. This is just two cases, so it shows a possible link but not proof that the drugs cause this harm. The findings are important because these cancer drugs are widely used, and doctors need to watch for early signs of kidney injury.

Who did this work

Roberta Fenoglio (Ospedale San Giovanni Bosco) · S. Cortazzi (Ospedale San Giovanni Bosco) · E. Tringali (Ospedale San Giovanni Bosco) · G. Del Vecchio (Ospedale San Giovanni Bosco) · E. De Simone (Ospedale San Giovanni Bosco) · S. Sciascia (Ospedale San Giovanni Bosco) · A. Barreca (University of Turin) · D. Roccatello (Ospedale San Giovanni Bosco)

Source

Paper · OpenAlex, CKD works · 2026-08-28
https://doi.org/10.1186/s12882-026-05242-z