← brief for 2026-08-28 · Regeneration & devices

Time-restricted feeding reverses kidney fibrosis through reduced CD8+ T cell infiltration in obese mice.

Article D Peer reviewed Preclinical

Key takeaways

In obese mice, limiting eating to 10 hours a day for two weeks reversed kidney scarring and lowered certain immune cells in the kidney. This was not tested in people, so it is unknown if time-restricted eating would help humans with kidney disease.

Who did this work

Edell CJ · Erickson JD · Liu X · Walker SC · Colson J · Heim M · Nagila P · Moore KH · Kemp KM · Hyndman K · Meza-Perez S · Randall TD

Source

Article · PubMed, CKD severity and reversal · 2026 Aug 20
https://pubmed.ncbi.nlm.nih.gov/42664422/