← brief for 2026-08-27 · Nutrition & lifestyle

Noncovalent SARS-CoV-2 main protease inhibitors targeting the catalytic dyad and primed substrate binding subsites.

Article D Peer reviewed Preclinical

Key takeaways

This lab study tested molecules that block a virus protein in test tubes and computer models — not people. It found some candidates might stop the virus from copying, but it has no data on kidney safety or effect in living things yet.

Who did this work

Bhandari D · Kovalevskaya K · Coates L · Jonsson CB · Parvathareddy J · Weiss KL · Aniana A · Louis JM · Bonnesen PV · Kovalevsky A

Source

Article · PubMed, Climate, heat and the kidney · 2026 Aug 14
https://pubmed.ncbi.nlm.nih.gov/42657162/