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Integration of multi-omics and network toxicology suggests potential mechanisms linking artificial sweeteners to chronic kidney disease

Paper D Peer reviewed Preclinical

Key takeaways

This is a computer and lab study looking at how artificial sweeteners might affect the kidney. Researchers combined large biological datasets with network models to guess which pathways sweeteners could disturb. This was done in data and cells, not in people, so it does not show that sweeteners harm anyone's kidneys. It points to things worth testing, nothing more.

Who did this work

Xilong Wang · 陈丽晨 · Zhibin Jiang · Dian Jin · Yining Chen · Yongheng Bai · Xiaodong Pan · Yong Cai · Jixiang Yuan

Source

Paper · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-08-26
https://doi.org/10.1186/s40360-026-01201-4