← brief for 2026-08-21 · Regeneration & devices

Sulforaphane mitigates behavioral deficits in experimental chronic kidney disease through regulation of Nrf2/NLRP3 inflammasome

Paper D Peer reviewed Preclinical

Key takeaways

In rats with kidney disease, sulforaphane (a compound in broccoli) lowered brain fog and inflammation by turning on a protective pathway — but this has not been tested in people yet.

Who did this work

Hend Samir Zakaria Mohammed (Alexandria University) · Mohamed T. Ghoneim (Alexandria University) · Doaa A. Ghareeb (Pharos University in Alexandria) · Aliaa A. Masoud (Alexandria University) · Sherouk S. Shams (Alexandria University)

Source

Paper · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-08-20
https://doi.org/10.1007/s00210-026-05831-7