← brief for 2026-08-10 · Slowing decline

Intensification of Blood Pressure Lowering Therapeutics Based on Diuretics Versus Usual Management for Uncontrolled Hypertension IN Patients With Moderate to Severe Chronic Kidney Disease

Trial No results yet Not peer reviewed

Key takeaways

This trial tests whether pushing blood pressure lower with water-pill (diuretic) treatment beats usual care in people with moderate to severe kidney disease and hard-to-control high blood pressure. High blood pressure is a top driver of kidney damage. It is enrolling now, so there are no results yet.

Who did this work

Run by University Hospital, Tours. Bénédicte Sautenet, MD (University Hospital, Tours)
Sites: Department of Nephrology, University Hospital of Angers · Department of Nephrology, University Hospital of Bordeaux · AUB Santé foundation, Brest · Department of Nephrology, University Hospital of Brest · Department of Nephrology, Hospital of Chalon-sur-Saône · Department of Nephrology, Hospital of Chartres

Source

Trial · ClinicalTrials.gov, CKD recruiting · 2026-08-03
https://clinicaltrials.gov/study/NCT05732727